KMID : 0364019920250070736
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Korean Journal of Thoracic and Cardiovascular Surgery 1992 Volume.25 No. 7 p.736 ~ p.738
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Effect of Nifedipine in Acute Episode of Postoperative Pulmonary Hypertension and Right Heart Failure
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Abstract
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We report the successful use of Nifedipine in the treatment of acute pulmonary hypertension in an young child after a cardiac operation. This patient had undergone patch closure of large ventricular septal defect. She had signs of severe
pulmonary
artery hypertension unresponsive to hyperventilation, oxygenation, sedation, and a myriad of vasoactive drugs. Nifedipine, 0.3mg/kg every 4 hours, effectively treated her pulmonary artery hypertension and allowed for a smooth postoperative course
and
positive cutcome. The drug lowered systemic diastolic pressure, but not systolic pressure.
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